Izzie Stevens got cancer, married Alex, survived the cancer, and then just disappeared in season six. Eventually, she returned for a second, admitting that she no longer felt Seattle was her home. Later, Alex was sent divorce papers, and now we know that Izzie secretly had Alex twins, lives on a ranch in Kansas, and became a surgical oncologist.
Katherine Heigl ‘s exit began largely in 2008, when she withdrew her name from the Emmy consideration because she did not feel the material deserved it. In 2010, the character completely disappeared. She said years ago that she would like to return to character, but Shonda Rhimes did not. “I’m done with that story,” she told TVLine in 2015.
Heigl, then a budding romcom star, continued to play in a few more romcoms before returning to television with Condition, then Doubt, and recently she joined Suit and the 2020 series Firefly Lane.
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